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From234US$ /night
Check-in
12Nov2025Select date
Check-out
13Nov2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

1528 Locust Street, Saint Louis, Missouri, United States, 63103

Rooms & Suites

21c Museum Hotel St Louis offers rooms with air conditioning, seating areas, wardrobes, and flat-screen TVs with streaming services. The Luxury Double Queen includes two queen beds and a bathtub. The Corner King Suite has a king bed and separate living area. The 21c King Suite is a two-story duplex with a fireplace, kitchenette, and personal fitness loft. All rooms feature Malin+Goetz toiletries, free Wi-Fi, and original artwork by Missouri-based artists.

Dining & Drinks

Idol Wolf serves Spanish-inspired tapas with Midwestern ingredients. 21c on the Rocks offers bourbon cocktails. Northwest Coffee provides locally roasted coffee, and Big Heart Tea Co. serves seasonal teas. In-room dining is available 24 hours.

Art & Wellness

The hotel features rotating contemporary art exhibitions, including installations like 'The Way Out West' and 'View Finder.' Locust Street Athletic and Swim Club has a historic indoor pool, sauna, steam rooms, and fitness center with Peloton bikes. Spa services include massages and yoga classes.

Location & Access

The hotel is in Downtown St Louis, 1 km from Busch Stadium and 2.5 km from the Gateway Arch. Nearby landmarks include Christ Church Cathedral (0.5 km) and Citygarden Sculpture Park (1 km). St Louis Lambert International Airport is 16 km away.

Services & Events

The hotel offers laundry service, 24-hour fitness access, and pet-friendly rooms. Meeting spaces include the Main Gallery with AV technology. Wedding packages feature catering by Idol Wolf. Group rates and personalized training sessions are available.

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Choose the Room

From cosy doubles to spacious family suites – all with flexible options, breakfast, and exclusive deals.
Corner King Room
2 persons
30 m² 
1 King-size bed
Shower
Heating
Deluxe King Room
2 persons
29 m² 
1 King-size bed
Shower
Heating
Deluxe King Suite Roll Shower Accessible
2 persons
47 m² 
1 King-size bed
Shower
Heating
Loft Two Queen Beds
2 persons
40 m² 
2 King Size Beds
Shower
Heating
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Getting around

All Transportation Options at a Glance

City Centre
Saint Louis600 m
Airports
Lambert (STL) 21.8 km
MidAmerica St. Louis/Scott Air Force Base (BLV) 40.8 km
Train
Union Station700 m
Bus
Bus stop200 m

Amenities

Thoughtfully designed amenities for a comfortable & memorable stay

General

  • No smoking on site
  • Free Wi-Fi
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • 24-hour security
  • Luggage storage
  • Locker room
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Coffee shop
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre
  • Billiard tables
  • Yoga class

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities

Children

  • Cots
  • Board games
  • Game room

Facilities for people with disabilities

  • Toilet for disabled

Spa & Leisure

  • Indoor swimming pool
  • Leisure/ TV room
  • Spa & wellness centre
  • Steam room
  • Jacuzzi
  • Massage

Room features

  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Terrace
  • Garden furniture

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
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Location

1528 Locust Street, Saint Louis, Missouri, United States, 63103
Map view
1528 Locust Street, Saint Louis, Missouri, United States, 63103
Nearby
Museum
City Museum
520 m
Museum
Campbell House Museum
90 m
Church
Christ Church Cathedral
430 m
1315 Chestnut St
Soldiers Memorial Military Museum
590 m
Aquarium
World Aquarium
400 m
Church
Centenary United Methodist Church
190 m
Night club
The Boom Boom Room
280 m
13th and Locust
Lucas Garden Park
350 m
Restaurants
The Last Kitchen
360 m
1501 Washington Ave Inside The Last Hotel
Red Oak Biscuits
310 m
1330 Washington Ave
Nara Cafe and Hookah Lounge
310 m
1326 Washington Ave
Flannery's
380 m
1324 Washington Ave
Rooftop Cafe at City Museum
400 m
701 N 15th St Fl 11
Lucas Park Grille
440 m
1234 Washington Avenue
Rosalita's Cantina
480 m
1235 Washington Avenue
Blondie's Coffee
450 m
1301 Washington Ave
Imo's Pizza
410 m
1828 Washington Ave
Papa John's Pizza
610 m
201 N Tucker Blvd Ste E
Bootleggin' BBQ
650 m
1933 Washington Ave
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Check-in
12Nov2025Select date
Check-out
13Nov2025Select date
Rooms and Guests2 Guests, 1 Room